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More Patient Info Guides

Home > Patient Info > Diabetes > Treatment Options

Diabetes Patient Info

 
  • Overview
  • Specialists
  • How to Prepare
  • Questions to Ask
  • What to Expect
  • Treatment Options
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Diabetes Treatment Options

While there is no cure for diabetes, a combination of diet, exercise and medication is effective in controlling blood sugar and preventing or delaying symptoms and diabetic related illness.

Medications for diabetics typically fall into two categories: oral hypoglycemics taken by mouth, and insulin which is injected into the body.

Oral Hypoglycemics

Class
Drug Names
How it Works
Biguandes
Metaformin

Decreases liver production

Helps with response to insulin


Sulfonylureas
Glimepiride
Glipizinzide
Glyburide
Nateglinide
Repaglinide

Increase insulin production by the pancreas

Lowers blood glucose levels


Thiazolidinediones
Pioglitazone
Rosiglitazone
Helps the body's response to insulin

DPP-4 Inhibitors
Sitagliptin
Saxagliptin

Increases insulin secretion.

Decreases release of glucagons, the pancreatic hormone that raises blood sugar.

Types of Insulin

Your insulin prescription will be determined by a number of factors.

  • Type of diabetes
  • How often you can check blood sugar
  • How often you give injections
  • Your age
  • Your body's response
  • Your lifestyle (diet, daily activities, exercise)
Type
When to Administer
What it Does
How Long it Works
Basal

Once or twice per day.

May be given in conjunction with oral medication or bolus insulin.

Controls glucose levels through the night and between meals.

Intermediate-acting

  • starts in 1–3 hrs
  • works for 12–16 hrs
  • NPH

Long-acting

  • starts in 1 hr
  • works for 20–26 hrs
  • glargine, detemir

Bolus (meal-time)

Given prior to meals

Usually in conjunction with basal insulin.

Regulates the spike of blood sugar levels after eating

Short-Acting

  • regular insulin
  • starts in 30–60 minutes
  • works for 5–8 hrs

Rapid-Acting

  • starts in 15 minutes
  • works for 3–5 hrs
  • lispro, aspart, glulisine

Pre-mixed

Given twice each day.

Administered prior to breakfast and dinner.

Regulates blood glucose between and after meals.

Combination of intermediate-acting with bolus insulin types.

  • starts in 30–60 minutes
  • work 10–16 hrs
  • with or without oral hypoglycemic drugs

Insulin Devices

Several device types are now available to inject insulin rather than using the standard needle and syringe.

Type
Insulin Pens
Insulin Pump
Injection Port
Insulin Jet Injector
What is it?
Shaped like a pen with a refilled and/or replaceable cartridge.

Size of a cell phone or deck of playing cards, the insulin pump is worn on a belt or in a pocket.

Gives a steady trickle amount of insulin throughout the day.

A tube is inserted beneath the skin for insulin injections.
Sends a fine spray into the skin at high pressure.

Advantages

Easy to use and disposable.

Some patients claim they are less painful than standard needles.

Predictable insulin levels and actions (long and intermediate-acting insulin are not used with the pump).

Decreases the number of skin punctures.

Insulin is injected fast.

With insulin needles, the syringe stays in the skin for 6 seconds to prevent insulin from leaking back through the injection site.

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